影片由加拿大演员、歌手罗伯·斯代法钮克自导自演，Alice Cooper、Iggy Pop、Carol Pope、Henry Rollins以及Moby等众多大牌客串。斯代法钮克扮演的乔伊是新人乐队The Winners的主唱。女贝斯手詹妮弗（杰西卡·派尔）在同一位吸血鬼一夜情今后拥有了神奇的性感魅力，使得乐队刹时征服台下的所有观众。The Winners成名在看，然而名为E…

ZOMBEX tells the story of a post-Katrina New Orleans as it deals with a new disaster, a zombie apocalypse. NOLA residents are no longer experiencing the depression and post-traumatic stress due to the trauma of the hurricane, thanks to the revolutionary ZOMBEX - a rogue, yet, "clinically-proven" anti-depressa…

本片是系列的收官之作，讲述了一群生化人反抗暴政的故事，更奇特的是，我记得片中有一位女生化人居然怀孕了。